Search on: GP120, HTLV-III 
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Descriptor English:   HIV Envelope Protein gp120 
Descriptor Spanish:   proteína gp120 de la envoltura del VIH 
Descriptor Portuguese:   Proteína gp120 do Envelope de HIV 
Synonyms English:   Envelope Glycoprotein gp120, HIV
HIV Envelope Glycoprotein gp120
HTLV III gp120
HTLV-III gp120
env Protein gp120, HIV
gp120 Envelope Glycoprotein, HIV
gp120(HIV)
gp120, HTLV-III  
Tree Number:   D12.776.964.775.325.164.249
D12.776.964.775.562.500.500
D12.776.964.970.880.325.164.249
D23.050.327.520.350
Definition English:   External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV. 
See Related English:   Peptide T
 
History Note English:   90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   24717 
Unique Identifier:   D015699 

Occurrence in VHL:
 

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